Single-Molecule Detection in Solution Methods and Applications

From Book News, Inc.
For their equally advanced colleagues, researchers from a number of disciplines report the latest developments in detecting single molecules and the impact of the technique in analytical chemistry, biology, and medicine. Among their topics are detection in liquids and on surfaces under ambient conditions, theoretical foundations, surface-enhanced Raman scattering, using the confocal laser scanning microscope, the spectroscopy of individual photosynthetic pigment- protein complexes, single-dye tracing for ultrasensitive microscopy on living cells, the chemistry of a single enzyme molecule, and specific nucleic acid sequences.Copyright © 2004 Book News, Inc., Portland, OR


Analytical Chemistry, November 2002
"Single-molecule detection and the field of nanoscience have expanded during the past 10 years. This book covers the gambit&"


Book Description
The detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years.
This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results.
This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme.


About the Author
Well known international researchers and specialists from USA, Canada, Germany, Netherlands
S.A. Soper is editor of "Single Molecules", Wiley-VCH

Boehmer, Martin (University of Regensburg, Germany)
Castro, Alonso (Los Alamos National Laboratory, NM, USA)
Dovichi. N. J. (University of Alberta, Canada)
Enderlein, Joerg (University of Regensburg, Germany)
Keller, Richard A. (Los Alamos National Laboratory, NM, USA)
Kneipp, Katrin (M.I.T., MA, USA)
Koehler, Juergen (Ludwig Maximilians University of Munich, Germany)
Nie, Shuming (University of Bloomington, IN, USA)
Sauer, Markus (University of Heidelberg, Germany)
Schmidt, Thomas (University of Leiden, The Netherlands)
Soper, Steve A. (Louisiana State University, LA, USA)
Thiel, Erwin (University of Siegen, Germany)
Wrachtrup, Joerg (Technical University of Chemnitz, Germany)
Yanagida, Toshio (Osaka University, Japan)
Zander, Christoph (University of Siegen, Germany)


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For their equally advanced colleagues, researchers from a number of disciplines report the latest developments in detecting single molecules and the impact of the technique in analytical chemistry, biology, and medicine. Among their topics are detection in liquids and on surfaces under ambient conditions, theoretical foundations, surface-enhanced Raman scattering, using the confocal laser scanning microscope, the spectroscopy of individual photosynthetic pigment- protein complexes, single-dye tracing for ultrasensitive microscopy on living cells, the chemistry of a single enzyme molecule, and specific nucleic acid sequences. Annotation c. Book News, Inc., Portland, OR (booknews.com)


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