Molecular Biotechnology: Principles and Applications of Recombinant DNA

ANNOTATION

The book contains predominantly color illustrations, with some black-and-white illustrations.

Covers both the underlying scientific principles and the wide-ranging industrial, agricultural, pharmaceutical, and biomedical applications of recombinant DNA technology.

FROM THE PUBLISHER

Completely revised and updated, the second edition of the best-selling Molecular Biotechnology: Principles and Applications of Recombinant DNA covers both the underlying scientific principles and the wide-ranging industrial, agricultural, pharmaceutical, and biomedical applications of recombinant DNA technology. Ideally suited as a text, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

SYNOPSIS

Written for advanced undergraduates and graduate students, this textbook covers both the underlying scientific principles and the industrial, agricultural, pharmaceutical, and biomedical applications of recombinant DNA technology. The authors teach at the University of Waterloo. Annotation (c)2003 Book News, Inc., Portland, OR

FROM THE CRITICS

Michael Cummings

This new edition has been extensively re-organized and updated, with a new chapter on the organisms used in biotechnology, and new material on the basic principles of molecular biology. Other chapters, especially those dealing with plant biotechnology, have been greatly expanded. The pedagogical value of the book has been enhanced by a great increase in the number of figures and tables. The creation of the field of biotechnology by the fusion of recombinant DNA technology with industrial microbiology has generated a need for courses and textbooks in this new discipline. This second edition text fills the need for a well-organized and logical presentation of the principles and applications of biotechnology. It is intended as a text for an advanced undergraduate or beginning graduate course on biotechnology. This new edition should be one of the top choices for instructors and students. It can also serve as a supplement to courses in molecular biology, biochemistry, or genetics. The book is divided into four parts. In the first, the basics of recombinant DNA technology, the prokaryotic and eukaryotic biological systems used in biotechnology, and the production of proteins in prokaryotic and eukaryotic hosts are covered. In the second, the use of microbial systems in diagnostics, production of vaccines and therapeutic proteins, and the industrial/agricultural uses of biotechnology are discussed. Part Three includes chapters on the use of gene transfer in plants and animals, mapping of human genes, and gene therapy. The last section is an overview of regulation and patenting in the biotechnology industry. The strengths of this book are in Parts 2 and 4. In Part 2, the authorsprovide a detailed examination of how industrial methods are used in the production of therapeutic proteins such as human growth hormone, as well as vaccines and biopolymers. In Part 4, the regulation of recombinant DNA technology is discussed. This section includes the important topics of genetically modified food, the release of genetically engineered organisms, human gene therapy and the patenting of DNA sequences, and genetically modified organisms.

Ming-yuan Zhou

This book introduces and explains the new achievements of molecular biology and their applications in science and industry. The purpose is to help readers understand what molecular biotechnology actually is as a scientific discipline, how the research in this area is conducted, and how this technology may realistically impact on our lives in the future. The book meets the author's objectives. Targeted especially for students in life sciences, such as molecular genetics, biochemistry, microbiology, pathology, pharmacology, etc., it will also be useful for those who have been in this field for many years. The authors are very solid and credible in their respective areas. This book is very clear in its definition of the terminology and concepts of molecular biology. It includes numerous charts, figures, and tables to illustrate various strategies. The references are appropriate and precise. This is a very useful book for students and the people who work in the field of molecular biology and can be used either as a textbook or as supplementary reading material. It brings together theoretical concepts of molecular biology and links them to practice issues. It helps fill the need for more application-oriented books in modern molecular biology and genetics.

Doody Review Services

Reviewer: Michael Cummings, PhD (University of Illinois at Chicago)Description: This new edition has been extensively re-organized and updated, with a new chapter on the organisms used in biotechnology, and new material on the basic principles of molecular biology. Other chapters, especially those dealing with plant biotechnology, have been greatly expanded. The pedagogical value of the book has been enhanced by a great increase in the number of figures and tables. Purpose: The creation of the field of biotechnology by the fusion of recombinant DNA technology with industrial microbiology has generated a need for courses and textbooks in this new discipline. This second edition text fills the need for a well-organized and logical presentation of the principles and applications of biotechnology. Audience: It is intended as a text for an advanced undergraduate or beginning graduate course on biotechnology. This new edition should be one of the top choices for instructors and students. It can also serve as a supplement to courses in molecular biology, biochemistry, or genetics. Features: The book is divided into four parts. In the first, the basics of recombinant DNA technology, the prokaryotic and eukaryotic biological systems used in biotechnology, and the production of proteins in prokaryotic and eukaryotic hosts are covered. In the second, the use of microbial systems in diagnostics, production of vaccines and therapeutic proteins, and the industrial/agricultural uses of biotechnology are discussed. Part Three includes chapters on the use of gene transfer in plants and animals, mapping of human genes, and gene therapy. The last section is an overview of regulation and patenting in the biotechnology industry. Assessment: The strengths of this book are in Parts 2 and 4. In Part 2, the authors provide a detailed examination of how industrial methods are used in the production of therapeutic proteins such as human growth hormone, as well as vaccines and biopolymers. In Part 4, the regulation of recombinant DNA technology is discussed. This section includes the important topics of genetically modified food, the release of genetically engineered organisms, human gene therapy and the patenting of DNA sequences, and genetically modified organisms.

Booknews

A text for courses in biotechnology and applied molecular biology, covering both the underlying scientific principles and the wide- ranging industrial, agricultural, pharmaceutical, and biomedical applications of recombinant DNA technology. The volume is divided into four major sections: fundamentals of molecular biotechnology, microbial systems, eukaryotic systems, and regulating and patenting molecular biotechnology. Includes a 34-page glossary. Annotation c. Book News, Inc., Portland, OR (booknews.com)

RATING

4 Stars! from Doody

ACCREDITATION