Human Molecular Genetics

From Book News, Inc.
Strachan (scientific director, Institute for Human Genetics; human molecular genetics, University of Newcastle, UK) and Read (human genetics, Manchester University) have integrated the latest data from the Human Genome Project and have included new chapters on cells and development and on functional genomics, proteomics, and bioinformatics in this third edition of a text bridging elementary textbooks and the research literature. There is rewritten and reorganized coverage of complex disease genetics, and increased emphasis on gene function and on applications of genetic knowledge and ethical issues. Material is written so that those with relatively little background can appreciate the latest research.Copyright © 2004 Book News, Inc., Portland, OR


Journal of Medical Genetics, 2004, #41
"…Timely, up to date, and has enormous and comprehensive coverage… …This book is a good buy, an excellent read..."


Book Description
Following the completion of the Human Genome Project the content and organization of the third edition of Human Molecular Genetics (HMG) has been thoroughly revised. PART ONE (CHAPTERS 1-7) covers basic material on DNA structure and function, chromosomes, cells and development, pedigree analysis and the basic techniques used in the laboratory. PART TWO (CHAPTERS 8-12) discusses the various genome sequencing projects and the insights they provide into the organization, expression, variation and evolution of our genome. PART THREE (CHAPTERS 13-18) focuses on mapping, identifying and diagnosing the genetic causes of mendelian and complex diseases and cancer. PART FOUR (CHAPTERS (19-21) looks at the wider horizons of functional genomics, proteomics, bioinformatics, animal models and therapy. There are new chapters on cells and development and on functional genomics. The sections on complex diseases have been completely rewritten and reorganized, as has the chapter on Genome Projects. Other changes include a new section on molecular phylogenetics (Chapter 12) and the introduction of ‘Ethics Boxes’ to discuss some of the implications of the new knowledge. Virtually every page has been revised and updated to take account of the stunning developments of the past four years since the publication of the last edition of Human Molecular Genetics.


Book Info
Univ. of Newcastle, UK. Textbook focuses on the new knowledge in human molecular genetics since the Human Genome Project. Includes new chapters on cells and development and on functional genomics, proteomics, and bioinformatics. Emphasis is placed on gene function and on applications of genetic knowledge, including ethical issues. Previous edition: c1999.


The publisher, John Wiley & Sons
A complete, up-to-the-minute account of human molecular genetics from basic principles to current practice. Designed to engage and motivate students the text covers the organization, expression and evolution of the human genome. Features a comprehensive chapter on the latest progress in the Human Genome Project.


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Provides introductory material on DNA and chromosomes and describes principles and applications of cloning and molecular hybridization, then presents a guide to the structure, evolution, and mutational instability of the human genome and human genes, and examines mapping of the human genome, study of genetic diseases, and dissection and manipulation of genes. This second edition contains new material on cell types, DNA microarrays, and how to obtain the latest data from Web-based resources. This edition also features the early use of hierarchical figures and flow charts to introduce principles described in later chapters, and a two-column layout to improve clarity. Strachan and Read teach genetics at the University of Newcastle, UK, and the University of Manchester, UK. Annotation c. Book News, Inc., Portland, OR (booknews.com)


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