BLAST
- Book Review,
by Ian Korf, et al
From Book News, Inc.
Intended for both students and researchers working in bioinformatics, this guide reviews the theory behind the molecular biology, computer science, and statistics that form the foundation of the basic local alignment search tool (Blast) for finding similarities between biological sequences, explains how to design and interpret Blast experiments, and demonstrates the application of NCBI-Blast and WU- Blast software in high throughput settings. The programming examples are written in Perl.Copyright © 2004 Book News, Inc., Portland, OR
Book Description
Sequence similarity is a powerful tool for discovering biological function. Just as the ancient Greeks used comparative anatomy to understand the human body and linguists used the Rosetta stone to decipher Egyptian hieroglyphs, today we can use comparative sequence analysis to understand genomes. BLAST (Basic Local Alignment Search Tool), is a sophisticated software package for rapid searching of nucleotide and protein databases. It is one of the most important software packages used in sequence analysis and bioinformatics. Most users of BLAST, however, seldom move beyond the program's default parameters, and never take advantage of its full power. BLAST is the only book completely devoted to this popular suite of tools. It offers biologists, computational biology students, and bioinformatics professionals a clear understanding of BLAST as well as the science it supports. This book shows you how to move beyond the default parameters, get specific answers using BLAST, and how to interpret your results. The book also contains tutorial and reference sections covering NCBI-BLAST and WU-BLAST, background material to help you understand the statistics behind BLAST, Perl scripts to help you prepare your data and analyze your results, and a wealth of tips and tricks for configuring BLAST to meet your own research needs.
Buy from Amazon
Compare Prices
|
|
Home
