Genes VII FROM THE PUBLISHER
"Genes VII", the 7th of the "Genes" texts, gives an integrated account of the structure and function of genes, providing a synthesis and continuing the greater emphasis on how genes function in their biological context. In a change to all previous editions, which started with a traditional analysis of formal genetics, this 7th edition has been organized to present the subject in the context of the eukaryotic gene as revealed in the 1990s, an analysis based directly on the molecular properties of the gene itself.
SYNOPSIS
The power of direct analysis of the genome has made a significant difference in the approach of Genes VII. In a departure from previous editions, which started with a traditional analysis of formal genetics, the new edition begins with the molecular properties of the gene itself. The text is now reorganized to begin with the concept of genes as a segment of DNA coding for protein, and then proceeds directly to the characterization of the genome in terms of its content of genes.
Integrated Approach
Genes VII first explains the structure and function of the gene as a means to revealing the operation of the genome as a whole, and offers an integrated approach to prokaryotes and eukaryotes. The gene is considered from all aspects, including:
Basic forms
The numbers and relationships among genes in a genome
Their packaging into chromosomes
The process of gene expression from transcription through translation
The reproduction and safeguarding of the gene structure
Aspects of the overall circuitry through which genotype determines phenotype
Streamlined, Full-Color Design
Genes VII has been considerably restructured and reorganized to highlight the latest research and technology. It contains more that 800 full color illustrations that are extremely useful in teaching the key concepts presented in the book.
Genes VII Contains New, Groundbreaking Information On:
New technologies that count and compare expressed genes
Accessory proteins (chaperones)
The role of the proteasome
Licensing
Reverse translocation
Connections between repair and recombination systems and human diseases
Connections between the structure of chromosomal material and control of gene expression in eukaryotes
The process of X chromosome inactivation
Imprinting
Control of gene expression by epigenetic changes
The enzymatic activities that control chromatin structure and affect the regulatory process
Archeael enzymes
The mechanism of RNA editing in lower eukaryotes
The role of RAG genes
Interactions within and between pathways
The use of protein degradation to control passage through the cell cycle
Programmed cell death
Telomerase and its role in carcinogenesis. And much more
Extensively updated and restructured to present the most current research even more clearly and concisely.
Smart new design presents the material even more clearly than before.
Profusely illustrated with over 800 full colour illustrations.
This is the most authoritative textbook available on his subject.
Logically structured easy to follow and learn from.
All key concepts are well illustrated with extensive use of overview figures that summarize large amounts of work.